142 research outputs found
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Treatment of mixed waste coolant
The primary processes used at Lawrence Livermore National Laboratory (LLNL) for treatment of radioactively contaminated machine coolants are industrial waste treatment and in situ carbon adsorption. These two processes simplify approaches to meeting the sanitary sewer discharge limits and subsequent Land Disposal Restriction criteria for hazardous and mixed wastes (40 CFR 268). Several relatively simple technologies are used in industrial water treatment. These technologies are considered Best Demonstrated Available Technologies, or BDAT, by the Environmental Protection Agency. The machine coolants are primarily aqueous and contain water soluble oil consisting of ethanol amine emulsifiers derived from fatty acids, both synthetic and natural. This emulsion carries away metal turnings from a part being machined on a lathe or other machining tool. When the coolant becomes spent, it contains chlorosolvents carried over from other cutting operations as well as a fair amount of tramp oil from machine bearings. This results in a multiphasic aqueous waste that requires treatment of metal and organic contaminants. During treatment, any dissolved metals are oxidized with hydrogen peroxide. Once oxidized, these metals are flocculated with ferric sulfate and precipitated with sodium hydroxide, and then the precipitate is filtered through diatomaceous earth. The emulsion is broken up by acidifying the coolant. Solvents and oils are adsorbed using powdered carbon. This carbon is easily separated from the remaining coolant by vacuum filtration
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Meeting new air standards with a volatile organic treatment train
The U.S. Environmental Protection Agency (EPA) issued the second phase of the organic air emission standards for hazardous waste treatment, storage, and disposal facilities (TSDFs) and hazardous waste generators in December 1994. These standards (referred to as the Subpart CC standards) are designed to further reduce organic air emissions from hazardous waste management activities. To comply with these new air standards, Lawrence Livermore National Laboratory (LLNL) is designing a volatile organic removal and destruction treatment train to modify its existing Waste Water Treatment Tank Farm (hereafter called Tank Farm). LLNL`s Tank Farm consists of six, 7,000-L open-top tanks used to store and treat aqueous low-level radioactive, mixed, and hazardous waste before discharging it to the local publicly owned treatment works. The waste stored and treated in the tanks have elevated volatile organic constituent (VOC) concentrations. According to the Subpart CC standards, tanks handling waste with similar VOC concentrations must be retrofitted with a cover and an emission control device for cover openings that achieves at least a 95% reduction in the total organic content of the vented gas stream. However, LLNL concluded that the removal and destruction of VOCs from waste before they enter the Tank Farm would demonstrate compliance with the Subpart CC standards more effectively and be more cost effective than installation of air emission control devices on the Tank Farm. LLNL has designed this removal and destruction technique to consist of an air stripper, high-efficiency particulate air (HEPA) filter, catalytic oxidizer, scrubber, and mist eliminator
Citizen Science 2.0 : Data Management Principles to Harness the Power of the Crowd
Citizen science refers to voluntary participation by the general public in scientific endeavors. Although citizen science has a long tradition, the rise of online communities and user-generated web content has the potential to greatly expand its scope and contributions. Citizens spread across a large area will collect more information than an individual researcher can. Because citizen scientists tend to make observations about areas they know well, data are likely to be very detailed. Although the potential for engaging citizen scientists is extensive, there are challenges as well. In this paper we consider one such challenge â creating an environment in which non-experts in a scientific domain can provide appropriate and accurate data regarding their observations. We describe the problem in the context of a research project that includes the development of a website to collect citizen-generated data on the distribution of plants and animals in a geographic region. We propose an approach that can improve the quantity and quality of data collected in such projects by organizing data using instance-based data structures. Potential implications of this approach are discussed and plans for future research to validate the design are described
Predicted Infrared and Raman Spectra for Neutral Ti_8C_12 Isomers
Using a density-functional based algorithm, the full IR and Raman spectra are
calculated for the neutral Ti_8C_12 cluster assuming geometries of Th, Td, D2d
and C3v symmetry. The Th pentagonal dodecahedron is found to be dynamically
unstable. The calculated properties of the relaxed structure having C3v
symmetry are found to be in excellent agreement with experimental gas phase
infrared results, ionization potential and electron affinity measurements.
Consequently, the results presented may be used as a reference for further
experimental characterization using vibrational spectroscopy.Comment: 6 pages, 5 figures. Physical Review A, 2002 (in press
On the role of the upper part of words in lexical access : evidence with masked priming
More than 100 years ago, Huey (1908) indicated that the upper part of words was more relevant for perception than the lower part. Here we examined whether mutilated words, in their upper/lower portions (e.g., , , , ), can automatically access their word units in the mental lexicon. To that end, we conducted four masked repetition priming experiments with the lexical decision task. Results showed that mutilated primes produced a sizeable masked repetition priming effect. Furthermore, the magnitude of the masked repetition priming effect was greater when the upper part of the primes was preserved than when the lower portion was preserved âthis was the case not only when the mutilated words were presented in lowercase but also when the mutilated words were presented in uppercase. Taken together, these findings suggest that the front-end of computational models of visual-word recognition should be modified to provide a more realistic account at the level of letter features.The research reported in this article has been partially supported by Grant PSI2008-04069/PSIC and CONSOLIDER-INGENIO2010 CSD2008-00048 from the Spanish Ministry of Science and Innovation and by Grant PTDC/PSI-PCO/104671/2008 from the Portuguese Foundation for Science and Technology
The PHENIX Experiment at RHIC
The physics emphases of the PHENIX collaboration and the design and current
status of the PHENIX detector are discussed. The plan of the collaboration for
making the most effective use of the available luminosity in the first years of
RHIC operation is also presented.Comment: 5 pages, 1 figure. Further details of the PHENIX physics program
available at http://www.rhic.bnl.gov/phenix
New insights into the genetic etiology of Alzheimer's disease and related dementias
Characterization of the genetic landscape of Alzheimer's disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/'proxy' AD cases and 677,663 controls. We found 75 risk loci, of which 42 were new at the time of analysis. Pathway enrichment analyses confirmed the involvement of amyloid/tau pathways and highlighted microglia implication. Gene prioritization in the new loci identified 31 genes that were suggestive of new genetically associated processes, including the tumor necrosis factor alpha pathway through the linear ubiquitin chain assembly complex. We also built a new genetic risk score associated with the risk of future AD/dementia or progression from mild cognitive impairment to AD/dementia. The improvement in prediction led to a 1.6- to 1.9-fold increase in AD risk from the lowest to the highest decile, in addition to effects of age and the APOE Δ4 allele
Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.
BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362
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